Absent 18F-FDG Uptake in the Brain-Unsuspected Brain Death.

Mette Abildgaard Pedersen, Søren Jensen-Fangel, Edith Nielsen, Per Borghammer, Mikkel Holm Vendelbo

Clinical nuclear medicine 2020 Oct

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Brain death is the complete, irreversible cessation of brain function, including the capacity for brainstem, respiratory, and vegetative activities. It is a clinical diagnosis that can be supplemented with brain perfusion imaging. Absent cerebral blood flow can be visualized with CT angiography or perfusion scintigraphy. F-FDG PET/CT, visualizing glucose uptake, is another approach that has been shown to indicate brain death in small case series. We here present a case with unsuspected absent F-FDG uptake and thus no metabolic activity, in the brain. The patient was declared brain dead later the same day.

Citation

Mette Abildgaard Pedersen, Søren Jensen-Fangel, Edith Nielsen, Per Borghammer, Mikkel Holm Vendelbo. Absent 18F-FDG Uptake in the Brain-Unsuspected Brain Death. Clinical nuclear medicine. 2020 Oct;45(10):e433-e434