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    Green iguanas are arboreal lizards, common as pet animals and in captivity. Knowledge of neoplasms in iguanas is scarce, and a challenge to their prevention, treatment, and prognosis. A captive green iguana showed a pigmented nasal exophytic neoplasm. Tumor cells were spindle-shaped to epithelioid with a variable amount of dark-brown or black granular melanin within the cytoplasm, and also presented cytoplasmic positivity for Melan-A and S100. Transmission electron microscopy evidenced intracytoplasmic melanosomes and premelanosomes and provided a definitive diagnosis of a nasal melanophoroma. Full characterization of the clinicopathological and ultrastructural features of the melanophoroma may contribute to the limited knowledge concerning cutaneous neoplasms in green iguanas. Copyright © 2020 Elsevier Inc. All rights reserved.

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    Isabel Luana de Macêdo, Davi Emanuel Ribeiro de Sousa, Líria Queiroz Luz Hirano, Khesller Patrícia Olazia Name, Sônia Nair Báo, Márcio Botelho de Castro. Nasal Melanophoroma in a Captive Green Iguana (Iguana Iguana). Topics in companion animal medicine. 2020 Nov;41:100463

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    PMID: 32823162

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