Dramatic Recovery from Cardiovascular Collapse: Paclitaxel as an Urgent Treatment for Primary Cardiac Angiosarcoma.

Toshio Suzuki, Yoshiyuki Yamamoto, Noriaki Sakamoto, Hideo Suzuki, Kazuko Tajiri, Tomoko Ishizu, Yasuhiro Fujisawa, Masayuki Noguchi, Masaki Ieda, Yuji Hiramatsu, Ikuo Sekine

Internal medicine (Tokyo, Japan) 2021 Jan 01

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We herein report three patients with cardiac angiosarcoma who were directly admitted to the intensive-care unit for hemodynamic instability with circulatory collapse. Using a multidisciplinary cardio-oncologic approach, we diagnosed their condition as angiosarcoma by an invasive biopsy and urgently started weekly paclitaxel administration despite their poor performance status. Their vital signs were soon stabilized, leading to the patients' discharge from the hospital. Although no treatment guidelines for cardiac angiosarcoma have been established, chemotherapy with paclitaxel can be an option for cases presenting with hemodynamic instability.

Citation

Toshio Suzuki, Yoshiyuki Yamamoto, Noriaki Sakamoto, Hideo Suzuki, Kazuko Tajiri, Tomoko Ishizu, Yasuhiro Fujisawa, Masayuki Noguchi, Masaki Ieda, Yuji Hiramatsu, Ikuo Sekine. Dramatic Recovery from Cardiovascular Collapse: Paclitaxel as an Urgent Treatment for Primary Cardiac Angiosarcoma. Internal medicine (Tokyo, Japan). 2021 Jan 01;60(1):67-71