Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Hypochlorite, as one of reactive oxygen species, has drawn much attention due to its essential roles in special biological events and disorders. The exogenous hypochlorite remains a risk for human, animals and plants. In this work, a novel water soluble quinolin-containing nitrone derivative T has been developed for fluorometric sensing hypochlorite. The response mechanism of T towards ClO- was reported for the first time. In comparison with the reported sensors for ClO-, the sensor T in this work exhibited advantages including high selectivity (80 fold over other analytes), rapid response (within 5 s) and lipid-water distribution transformation (LogP from 2.979 to 6.131). Further biological applications suggested that T was capable of monitoring both exogenous and endogenous ClO- in living cells. The imaging in Arabidopsis thaliana indicated that the absorption and transmission of ClO- in plant could be monitored by this sensor through the chlorine-related mechanism. This work might raise referable information for further investigations in the physiological and pathological events in both tumor and plants. Copyright © 2020 Elsevier B.V. All rights reserved.


Zi-Xuan Zeng, Jin Gu, Ya-Ni Liu, Dong-Dong Li, Yu-Shun Yang, Bao-Zhong Wang, Hai-Liang Zhu. A fluorescent sensor for selective detection of hypochlorite and its application in Arabidopsis thaliana. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Jan 05;244:118830

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 32858451

View Full Text