A fluorescent sensor for selective detection of hypochlorite and its application in Arabidopsis thaliana.

Zi-Xuan Zeng, Jin Gu, Ya-Ni Liu, Dong-Dong Li, Yu-Shun Yang, Bao-Zhong Wang, Hai-Liang Zhu

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2021 Jan 05

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Hypochlorite, as one of reactive oxygen species, has drawn much attention due to its essential roles in special biological events and disorders. The exogenous hypochlorite remains a risk for human, animals and plants. In this work, a novel water soluble quinolin-containing nitrone derivative T has been developed for fluorometric sensing hypochlorite. The response mechanism of T towards ClO- was reported for the first time. In comparison with the reported sensors for ClO-, the sensor T in this work exhibited advantages including high selectivity (80 fold over other analytes), rapid response (within 5 s) and lipid-water distribution transformation (LogP from 2.979 to 6.131). Further biological applications suggested that T was capable of monitoring both exogenous and endogenous ClO- in living cells. The imaging in Arabidopsis thaliana indicated that the absorption and transmission of ClO- in plant could be monitored by this sensor through the chlorine-related mechanism. This work might raise referable information for further investigations in the physiological and pathological events in both tumor and plants. Copyright © 2020 Elsevier B.V. All rights reserved.

Citation

Zi-Xuan Zeng, Jin Gu, Ya-Ni Liu, Dong-Dong Li, Yu-Shun Yang, Bao-Zhong Wang, Hai-Liang Zhu. A fluorescent sensor for selective detection of hypochlorite and its application in Arabidopsis thaliana. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Jan 05;244:118830