Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations.

Mehdi Maghbooli, Majid Ghaffarpour, Taher Ghazizadeh, Nazanin Azizi Shalbaf, Ghazal MalekMahmoudi

Neurology India 2020 Jul-Aug

filter terms:

Progressive external ophthalmoplegia (PEO) is a slowly progressive myopathy characterized by extraocular muscles involvement, leading to frozen eyes without diplopia. The pattern of inheritance may be mitochondrial, autosomal dominant or, rarely, autosomal recessive. Sporadic forms were also reported. Muscular involvement other than extraocular muscles may occur with varying degrees of weakness, but this mostly happens many years after the disease begins. There are also scattered data about systemic signs besides ophthalmoplegia. This article aims to review non-ophthalmic findings of PEO from a clinicogenetical point of view.

Citation

Mehdi Maghbooli, Majid Ghaffarpour, Taher Ghazizadeh, Nazanin Azizi Shalbaf, Ghazal MalekMahmoudi. Clinicogenetical Variants of Progressive External Ophthalmoplegia - An Especial Review of Non-ophthalmic Manifestations. Neurology India. 2020 Jul-Aug;68(4):760-768