Correlation Engine 2.0
Clear Search sequence regions


  • acc (2)
  • africa (2)
  • africa northern (1)
  • alphavirus (1)
  • antibodies (2)
  • arthralgia (1)
  • arthritis (1)
  • asia (2)
  • avian (2)
  • birds (4)
  • blood (3)
  • cases (4)
  • consensus sequences (1)
  • culex (4)
  • diagnosis (4)
  • dna polymerase (1)
  • dry ice (1)
  • england (1)
  • factors (1)
  • fast (1)
  • fever (1)
  • finland (34)
  • forests (2)
  • genbank (3)
  • genomes (1)
  • genotypes (1)
  • hamster (1)
  • hock (1)
  • igg (2)
  • igm (2)
  • israel (1)
  • kenya (1)
  • layer (1)
  • life cycle (1)
  • markov chain (1)
  • mosquito bites (1)
  • myalgia (1)
  • new england (1)
  • nucleic acids (2)
  • oceania (2)
  • ochlerotatus (16)
  • octenol (1)
  • patient (7)
  • pcr (4)
  • period (1)
  • phase (2)
  • probabilities (1)
  • rash (1)
  • reagents (2)
  • registry (3)
  • research (3)
  • risk factors (1)
  • rna (10)
  • rt pcr (4)
  • russia (2)
  • samples study (3)
  • saudi arabia (1)
  • sequence analysis (1)
  • serodiagnosis (4)
  • serum (15)
  • serum albumin (1)
  • sindbis virus (64)
  • skin lesions (1)
  • south africa (2)
  • spp (4)
  • strain (8)
  • sweden (6)
  • tree (3)
  • trizol (1)
  • viral rna (1)
  • viremia (1)
  • virus rna (1)
  • virus west nile (1)
  • Sizes of these terms reflect their relevance to your search.

    Sindbis virus (SINV) is a mosquito-borne avian hosted virus that is widely distributed in Europe, Africa, Asia, and Oceania. Disease in humans is documented mainly from Northern Europe and South Africa and associated with genotype I. In 2018 under extremely warm climatic conditions, a small outbreak of 71 diagnosed SINV infections was recorded in Finland. We screened 52 mosquito pools (570 mosquitoes) and 223 human sera for SINV with real-time RT-PCR and the positive samples with virus isolation. One SINV strain was isolated from a pool (n = 13) of genus Ochlerotatus mosquitoes and three strains from patient serum samples. Complete genome analysis suggested all the isolates to be divergent from one another and related to previous Finnish, Swedish, and German strains. The study provides evidence of SINV strain transfer within Europe across regions with different epidemiological characteristics. Whether these are influenced by different mosquito genera involved in the transmission remains to be studied.

    Citation

    Essi M Korhonen, Maija T Suvanto, Ruut Uusitalo, Giulia Faolotto, Teemu Smura, Jussi Sane, Olli Vapalahti, Eili Huhtamo. Sindbis Virus Strains of Divergent Origin Isolated from Humans and Mosquitoes During a Recent Outbreak in Finland. Vector borne and zoonotic diseases (Larchmont, N.Y.). 2020 Oct 28;20(11):843-849

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 32898458

    View Full Text