Rare case of Ureaplasma parvum septic arthritis in an immunocompetent patient.

Abuzar Ali Asif, Moni Roy, Sharjeel Ahmad

BMJ case reports 2020 Sep 08

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Mycoplasmatacea family comprises two genera: Mycoplasma and Ureaplasma Ureaplasma parvum (previously known as U. urealyticum biovar 1) commonly colonises the urogenital tract in humans. Although Ureaplasma species have well-established pathogenicity in urogenital infections, its involvement in septic arthritis has been limited to prosthetic joint infections and immunocompromised individuals. We present a rare case of native right knee infection due to U. parvum identified using next-generation sequencing of microbial cell-free DNA testing and confirmed with PCR assays. This rare case of Ureaplasma septic arthritis was diagnosed using newer next-generation DNA sequencing diagnostic modalities and a literature review of prior cases, antibiotic coverage and antimicrobial resistance is incorporated as part of the discussion. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Citation

Abuzar Ali Asif, Moni Roy, Sharjeel Ahmad. Rare case of Ureaplasma parvum septic arthritis in an immunocompetent patient. BMJ case reports. 2020 Sep 08;13(9)