Iron-containing pathologies of the spleen: magnetic resonance imaging features with pathologic correlation.

Nikita Consul, Sidra Javed-Tayyab, Ajaykumar C Morani, Christine O Menias, Meghan G Lubner, Khaled M Elsayes

Abdominal radiology (New York) 2021 Mar

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Systemic and non-systemic pathologies that involve iron deposition within the spleen have characteristic features on MRI due to the susceptibility properties of deposited iron, or hemosiderin. These lesions will have signal loss on longer echo sequences due to the T2* effect when evaluated with dual-echo gradient-echo sequences. The pathophysiology of systemic and localized iron sequestration disease processes can elucidate an underlying diagnosis based on these imaging features in conjunction with clinical information.

Citation

Nikita Consul, Sidra Javed-Tayyab, Ajaykumar C Morani, Christine O Menias, Meghan G Lubner, Khaled M Elsayes. Iron-containing pathologies of the spleen: magnetic resonance imaging features with pathologic correlation. Abdominal radiology (New York). 2021 Mar;46(3):1016-1026