Correlation Engine 2.0
Clear Search sequence regions

filter terms:
  • carbon (7)
  • serum (1)
  • Sizes of these terms reflect their relevance to your search.

    Rational design of detection strategy is the key to high-performance fluorescence analysis. In this article, we found that the glucose-induced limitations can greatly enhance the fluorescence of functionalized carbon nanoparticles (CNPs), which are synthesized through one-step thermal pyrolysis method using phenylboronic acid derivative as the precursors. The glucose can assembly onto the surface of the CNPs to form a "shell", limiting the surfaces' intramolecular rotation and reducing non-radiative decay, which hence resulted in enhanced fluorescence of the CNPs. Under optimal conditions, the fluorescence intensity of the CNPs is nearly 70-fold enhanced, and the method has low detection limit (10 μM) and linear response in the concentration range from 50 μM to 2000 μM. Based on this interesting "target-triggered limitation-induced fluorescence enhancement" phenomenon, a simple and effective non-enzymatic fluorescence enhancement method was developed and successfully applied to the determination of glucose in spiked serum samples. This work provides new insight into the design of fluorescence-enhanced detection strategies based on the limitation-induced property. Copyright © 2020 Elsevier B.V. All rights reserved.


    Qiujun Lu, Ting Huang, Jieqiong Zhou, Yue Zeng, Cuiyan Wu, Meiling Liu, Haitao Li, Youyu Zhang, Shouzhuo Yao. Limitation-induced fluorescence enhancement of carbon nanoparticles and their application for glucose detection. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Jan 05;244:118893

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 32916589

    View Full Text