Qiujun Lu, Ting Huang, Jieqiong Zhou, Yue Zeng, Cuiyan Wu, Meiling Liu, Haitao Li, Youyu Zhang, Shouzhuo Yao
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2021 Jan 05Rational design of detection strategy is the key to high-performance fluorescence analysis. In this article, we found that the glucose-induced limitations can greatly enhance the fluorescence of functionalized carbon nanoparticles (CNPs), which are synthesized through one-step thermal pyrolysis method using phenylboronic acid derivative as the precursors. The glucose can assembly onto the surface of the CNPs to form a "shell", limiting the surfaces' intramolecular rotation and reducing non-radiative decay, which hence resulted in enhanced fluorescence of the CNPs. Under optimal conditions, the fluorescence intensity of the CNPs is nearly 70-fold enhanced, and the method has low detection limit (10 μM) and linear response in the concentration range from 50 μM to 2000 μM. Based on this interesting "target-triggered limitation-induced fluorescence enhancement" phenomenon, a simple and effective non-enzymatic fluorescence enhancement method was developed and successfully applied to the determination of glucose in spiked serum samples. This work provides new insight into the design of fluorescence-enhanced detection strategies based on the limitation-induced property. Copyright © 2020 Elsevier B.V. All rights reserved.
Qiujun Lu, Ting Huang, Jieqiong Zhou, Yue Zeng, Cuiyan Wu, Meiling Liu, Haitao Li, Youyu Zhang, Shouzhuo Yao. Limitation-induced fluorescence enhancement of carbon nanoparticles and their application for glucose detection. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Jan 05;244:118893
PMID: 32916589
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