Controllable Phosphorylation of Thioesters: Selective Synthesis of Aryl and Benzyl Phosphoryl Compounds.

The controllable phosphorylations of thioesters were developed. When the reaction was catalyzed by a palladium catalyst, aryl or alkenyl phosphoryl compounds were generated through decarbonylative coupling, while the benzyl phosphoryl compounds were produced through deoxygenative coupling when the reaction was carried out in the presence of only a base.

Citation

Kaiqiang Xu, Long Liu, Zhaohui Li, Tianzeng Huang, Kang Xiang, Tieqiao Chen. Controllable Phosphorylation of Thioesters: Selective Synthesis of Aryl and Benzyl Phosphoryl Compounds. The Journal of organic chemistry. 2020 Nov 20;85(22):14653-14663

PMID: 32924481

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