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Same Script, Different Cast: Different Cell Origins Shape Molecular Features and Therapeutic Response in Glioblastoma.
Cancer cell 2020 Sep 14Sizes of these terms reflect their relevance to your search.
Glioblastoma is heterogeneous in the molecular subtypes based on transcriptomic classification. In this issue of Cancer Cell, Wang et al. define a cell-lineage-based stratification model for glioblastoma, highlighting how the cell of origin generates distinct molecular landscapes and therapeutic vulnerabilities from identical driver mutations. Copyright © 2020 Elsevier Inc. All rights reserved.
Citation
Sihan Wu, Paul S Mischel. Same Script, Different Cast: Different Cell Origins Shape Molecular Features and Therapeutic Response in Glioblastoma. Cancer cell. 2020 Sep 14;38(3):311-313
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PMID: 32931740
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