A case of dapsone-induced methaemoglobinaemia.

Yee Ann Tan, Kai Choon Ng, Seng Wee Cheo, Tee Tat Khoo, Qin Jian Low

Clinical medicine (London, England) 2020 Sep

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Methaemoglobinaemia is an uncommon but potentially serious condition. It can be caused by congenital or acquired cause. Drug-induced methaemoglobinaemia is the commonest cause of acquired methaemoglobinaemia. The clinical signs and symptoms of methaemoglobinaemia include dyspnoea, desaturation, presence of saturation gap, headache, nausea and seizures depending on level of serum methaemoglobinaemia. We illustrate a case of dapsone-induced methaemoglobinaemia and its successful treatment by intravenous methylene blue. © Royal College of Physicians 2020. All rights reserved.

Citation

Yee Ann Tan, Kai Choon Ng, Seng Wee Cheo, Tee Tat Khoo, Qin Jian Low. A case of dapsone-induced methaemoglobinaemia. Clinical medicine (London, England). 2020 Sep;20(5):519-521