Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

As the primary catalyst of homologous recombination (HR) in vertebrates, RAD51 has been extensively studied in the context of repair of double-stranded DNA breaks (DSBs). With recent advances in the understanding of RAD51 function extending beyond DSBs, the importance of RAD51 throughout DNA metabolism has become increasingly clear. Here we review the suggested roles of RAD51 beyond HR, specifically focusing on their interplay with DNA replication and the maintenance of genomic stability, in which RAD51 function emerges as a double-edged sword. Copyright © 2020. Published by Elsevier Ltd.


Isabel E Wassing, Fumiko Esashi. RAD51: Beyond the break. Seminars in cell & developmental biology. 2021 May;113:38-46

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 32938550

View Full Text