Egg white hydrolyzate reduces mental fatigue: randomized, double-blind, controlled study.

Mariko Oe, Hisae Sakamoto, Hiroshi Nishiyama, Ryou Sasahara, Yasunobu Masuda, Mizuho Adachi, Tetsunari Nishiyama

BMC research notes 2020 Sep 18

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This study aimed to show that ingesting egg white hydrolyzate (EWH) could improve antioxidant capacity and reduce mental fatigue. Two clinical trials were conducted to examine the antioxidant capacity and the fatigue reduction function of EWH. In Study 1, 19 athlete students were received a single dose of EWH (5 g/day) or placebo. In Study 2, 74 athlete students ingested EWH (5 g/day) or placebo before training for 2 weeks. Single dose of EWH significantly increased the antioxidant ability compared with the placebo group (p < 0.05), and there was no significant difference between the groups in the oxidative stress test results on Study 1. Two-week intake of EWH significantly decreased mental fatigue compared with the placebo (p < 0.05). This study showed that ingesting EWH improved antioxidant capacity with a single dose and reduced mental fatigue after 2 weeks of ingestion. Trial Registration Japan Medical Association Center for Clinical Trials identifier; JMA-IIA00395 (Study1) and JMA-IIA00396 (Study2), both trials were retrospectively registered on 26 October, 2018.

Citation

Mariko Oe, Hisae Sakamoto, Hiroshi Nishiyama, Ryou Sasahara, Yasunobu Masuda, Mizuho Adachi, Tetsunari Nishiyama. Egg white hydrolyzate reduces mental fatigue: randomized, double-blind, controlled study. BMC research notes. 2020 Sep 18;13(1):443