Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma.

Mark A Baxter, Lindsay C Spender, Russell D Petty

British journal of cancer 2020 Nov

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A trial update confirms improved survival for prophylactic elective nodal irradiation and addition of erlotinib to definitive chemoradiotherapy in oesophageal squamous cell carcinoma (ESCC). High tumour EGFR protein expression shows promise to identify those who will benefit from erlotinib. This represents therapeutic progress, and has wider relevance for precision medicine strategies in ESCC.

Citation

Mark A Baxter, Lindsay C Spender, Russell D Petty. Combining precision medicine and prophylaxis in oesophageal squamous cell carcinoma. British journal of cancer. 2020 Nov;123(11):1585-1587