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This report summarizes the current multimodality treatment approaches for children with low- and high-grade gliomas, germinoma, and nongerminomatous germ cell tumors, and craniopharyngiomas used in the Children's Oncology Group (COG) and the International Society of Pediatric Oncology (SIOP). Treatment recommendations are provided in the context of historical approaches regarding the roles of surgery, radiation, and chemotherapy. Future research strategies for these tumors in both COG and SIOP are also discussed. © 2020 Wiley Periodicals LLC.


Paul Aridgides, Geert O Janssens, Steve Braunstein, Shauna Campbell, Matthew Poppe, Erin Murphy, Shannon MacDonald, Matthew Ladra, Claire Alapetite, Daphne Haas-Kogan. Gliomas, germ cell tumors, and craniopharyngioma. Pediatric blood & cancer. 2021 May;68 Suppl 2:e28401

PMID: 32960496

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