Trilateral Relationship: Ascaris, Microbiota, and Host Cells.

Ascariasis is a globally spread intestinal nematode infection of humans and a considerable concern in pig husbandry. Ascaris accomplishes a complex body migration from the intestine via the liver and lung before returning to the intestine. Tissue migration and the habitat shared with a complex microbial community pose the question of how the nematode interacts with microbes and host cells from various tissues. This review addresses the current knowledge of the trilateral relationship between Ascaris, its microbial environment, and host cells, and discusses novel approaches targeting these interactions to combat this widespread infection of livestock and man. Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Citation

Ankur Midha, Friederike Ebner, Josephine Schlosser-Brandenburg, Sebastian Rausch, Susanne Hartmann. Trilateral Relationship: Ascaris, Microbiota, and Host Cells. Trends in parasitology. 2021 Mar;37(3):251-262

Mesh Tags

PMID: 33008723

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