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Today, Coronavirus Disease 2019 (COVID-19) is a global public health emergency and vaccination measures to counter its diffusion are deemed necessary. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of the disease, unleashes a T-helper 2 immune response in those patients requiring intensive care. Here, we illustrate the immunological mechanism to train the immune system towards a more effective and less symptomatic T-helper 1 immune response, to be exploited against SARS-CoV-2. Copyright © 2020 Elsevier Ltd. All rights reserved.

Citation

Luca Roncati, Maria Vadalà, Veronica Corazzari, Beniamino Palmieri. COVID-19 vaccine and boosted immunity: Nothing ad interim to do? Vaccine. 2020 Nov 10;38(48):7581-7584

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PMID: 33071005

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