Supportive Care for Patients with Systemic Light Chain Amyloidosis.

Sandy W Wong, Teresa Fogaren

Hematology/oncology clinics of North America 2020 Dec

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Light chain amyloidosis is a disease in which clonal plasma cells produce toxic immunoglobulin light chains that form amyloid fibrils with deposition in organs, most commonly the heart and kidneys, but also the nervous system, gastrointestinal tract, and soft tissues. Treatment directed at the clonal cells eliminates light chain production and further deposition and may enable organ improvement and decrease the risk of organ failure. Supportive care manages the symptoms of organ involvement and the side effects of treatment. Supportive care also addresses the psychological and social issues that may arise in patients with light chain amyloidosis. Copyright © 2020 Elsevier Inc. All rights reserved.

Citation

Sandy W Wong, Teresa Fogaren. Supportive Care for Patients with Systemic Light Chain Amyloidosis. Hematology/oncology clinics of North America. 2020 Dec;34(6):1177-1191