MTORC1 activity is critical for tissue regeneration in multiple organs and contexts. In this issue of Developmental Cell, Miao et al. describe upstream regulators of mTORC1 activity which promote paligenosis, a process where mature cells de-differentiate to acquire stem cell activity in the face of injury. Copyright © 2020 Elsevier Inc. All rights reserved.
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Nicolette M Johnson, Christopher J Lengner. MTORC1 and the Rebirth of Stemness. Developmental cell. 2020 Oct 26;55(2):113-115
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PMID: 33108751
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