The international glycan repository GlyTouCan version 3.0.

Akihiro Fujita, Nobuyuki P Aoki, Daisuke Shinmachi, Masaaki Matsubara, Shinichiro Tsuchiya, Masaaki Shiota, Tamiko Ono, Issaku Yamada, Kiyoko F Aoki-Kinoshita

Nucleic acids research 2021 Jan 08

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Glycans serve important roles in signaling events and cell-cell communication, and they are recognized by lectins, viruses and bacteria, playing a variety of roles in many biological processes. However, there was no system to organize the plethora of glycan-related data in the literature. Thus GlyTouCan (https://glytoucan.org) was developed as the international glycan repository, allowing researchers to assign accession numbers to glycans. This also aided in the integration of glycan data across various databases. GlyTouCan assigns accession numbers to glycans which are defined as sets of monosaccharides, which may or may not be characterized with linkage information. GlyTouCan was developed to be able to recognize any level of ambiguity in glycans and uniquely assign accession numbers to each of them, regardless of the input text format. In this manuscript, we describe the latest update to GlyTouCan in version 3.0, its usage, and plans for future development. © The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

Citation

Akihiro Fujita, Nobuyuki P Aoki, Daisuke Shinmachi, Masaaki Matsubara, Shinichiro Tsuchiya, Masaaki Shiota, Tamiko Ono, Issaku Yamada, Kiyoko F Aoki-Kinoshita. The international glycan repository GlyTouCan version 3.0. Nucleic acids research. 2021 Jan 08;49(D1):D1529-D1533