Masahiko Isaka, Somporn Palasarn, Jariya Sakayaroj, Kitlada Srichomthong, Sutichai Nithithanasilp, Malipan Sappan
Phytochemistry 2021 JanThree previously undescribed limonoids, fulvifomins A-C, together with two known compounds, 6-deoxydetigloyl-swietenine acetate and methyl angolensate, were isolated from fruiting bodies of the wood-rot fungus Fulvifomes xylocarpicola (Hymenochaetaceae), growing on the mangrove tree Xylocarpus granatum (Meliaceae). The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data, and X-ray crystallographic analysis (for fulvifomin A). A number of similar limonoids have been isolated from higher plants of the family Meliaceae, including X. granatum. The present study represents a unique evidence that the associated basidiomycete also contains these limonoids. Fulvifomin B exhibited moderate antimalarial and antitubercular activites. Copyright © 2020 Elsevier Ltd. All rights reserved.
Masahiko Isaka, Somporn Palasarn, Jariya Sakayaroj, Kitlada Srichomthong, Sutichai Nithithanasilp, Malipan Sappan. Limonoids from fruiting bodies of the wood-rot basidiomycete Fulvifomes xylocarpicola associated with the mangrove tree Xylocarpus granatum. Phytochemistry. 2021 Jan;181:112555
PMID: 33142147
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