Knowledge gaps in candidaemia/invasive candidiasis in haematological cancer patients.

Arnaldo Lopes Colombo, Caroline Agnelli, Dimitrios P Kontoyiannis

The Journal of antimicrobial chemotherapy 2021 Feb 11

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As neutropenic patients with haematological cancer are not typically included in randomized controlled trials (RCTs) of candidaemia, there is low quality of evidence regarding the management of this common opportunistic mycosis in this patient population, which is at high risk for poor outcomes. Herein we identify the gaps in knowledge that are not addressed by the modern RCTs and candidaemia guidelines, and outline some considerations for the future clinical research agenda in candidaemia/invasive candidiasis in haematological patients. © The Author(s) 2020. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Citation

Arnaldo Lopes Colombo, Caroline Agnelli, Dimitrios P Kontoyiannis. Knowledge gaps in candidaemia/invasive candidiasis in haematological cancer patients. The Journal of antimicrobial chemotherapy. 2021 Feb 11;76(3):543-546