The diverse roles of T cell subsets in asthma.

T cells are coordinators of the immune response and have been shown to play a central role in the pathophysiology of asthma. A good understanding of the T cells functions in asthma is important for therapeutic reasons, in particular for the choice of biological treatments in severe asthma. Although classically considered a Th2 disease, it is now clear that other types of T cells contribute for the pathophysiology and the heterogeneity of asthma. We here review how the different subsets of T cells are involved in the different phenotypes/endotypes of asthma and how this may influence the treatment of the disease.

Citation

F S Regateiro, P Botelho Alves, A L Moura, J P Azevedo, D T Regateiro. The diverse roles of T cell subsets in asthma. European annals of allergy and clinical immunology. 2021 Sep;53(5):201-208

Mesh Tags

PMID: 33182992

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