Three new phenanthrenes from Pholidota chinensis Lindl. and their antibacterial activity.

Huihui Ti, Zixi Zhuang, Yan Li, Guozhu Wei, Fei Wang

Natural product research 2022 Apr

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Three new phenanthrenes were isolated from Pholidota chinensis Lindl. Their structures were elucidated on the basis of spectroscopic techniques and comparison of their data to the values reported in the literature. From the 95% EtOH extract, three new compounds, namely 9, 10-dihydro-2, 4, 6-trihydroxy-7-methoxyphenanthrene (1), 11-methoxyflaccidin (2), and 2-methoxy-3,7-dihydroxy-5H phenanthro[4,5-bcd] pyran (3), were identified. Compound 3 showed an MIC50 of 68.39 µM against Staphylococcus aureus subsp. Aureus.

Citation

Huihui Ti, Zixi Zhuang, Yan Li, Guozhu Wei, Fei Wang. Three new phenanthrenes from Pholidota chinensis Lindl. and their antibacterial activity. Natural product research. 2022 Apr;36(8):2056-2062