A new lignan from the stem bark of Fagraea fragrans Roxb.

Suthida Rattanaburi, Kaodeeya Kaikaew, Ramida Watanapokasin, Souwalak Phongpaichit, Wilawan Mahabusarakamb

Natural product research 2022 Apr

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A new lignan, named fagraeanolide (1), and 14 known compounds were isolated from the stem bark of Fagraea fragrans Roxb. Their structures were determined by spectroscopic methods. Fagraeanolide is the first identified oxofurofuran lignan from the genus Fagraea, whileβ-boswelic acid (4), gentiogenol (5), 3-(4-hydroxy-3-methoxyphenyl)-acrylic acid octacosyl ester (7) and pinoresinol (14) were isolated from this plant for the first time. The crude extract of F. fragrans was not toxic to cell lines. The isolated compounds showed no antibacterial activity.

Citation

Suthida Rattanaburi, Kaodeeya Kaikaew, Ramida Watanapokasin, Souwalak Phongpaichit, Wilawan Mahabusarakamb. A new lignan from the stem bark of Fagraea fragrans Roxb. Natural product research. 2022 Apr;36(7):1851-1856