Correlation Engine 2.0
Clear Search sequence regions

  • antiandrogen (1)
  • antigen (3)
  • bone neoplasms (1)
  • cancer (1)
  • ganglia (3)
  • humans (1)
  • man (1)
  • metastases (1)
  • neuritis (1)
  • osseous disease (1)
  • patient (1)
  • positron (1)
  • prostate (4)
  • PSMA (3)
  • sciatic nerve (1)
  • segment (2)
  • Sizes of these terms reflect their relevance to your search.

    A 74-year-old man with a history of prostate cancer with proven osseous metastatic disease underwent Ga-prostate-specific membrane antigen (PSMA) PET/CT under antiandrogen therapy. The scan revealed a long segment of increased PSMA tracer uptake within the right sciatic nerve, which appeared edematous and swollen, and the respective ganglia. Clinically, the patient suffered from pain and paresis in the right leg. As infiltration of a long segment of a single nerve seems unlikely, primarily neuronal disease such as neuritis (induced by metastases or radiotherapy) was considered. The observed uptake of PSMA-targeting PET tracers may then represent a peripheral nerve disorder.


    Jasmin Mettler, Alexander Drzezga, Markus Dietlein, Tim Hucho, Carsten Kobe. Prostate-Specific Membrane Antigen Uptake in a Peripheral Nerve and Respective Ganglia on 68Ga-Prostate-Specific Membrane Antigen-HBED-CC PET/CT. Clinical nuclear medicine. 2021 Jan;46(1):69-70

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 33208621

    View Full Text