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Bayesian clinical trials are becoming popular owing to their adaptive, flexible, and versatile nature. Such trials typically require specification of the prior distribution and construction of the likelihood function; subsequently, inference is made on the basis of the posterior distribution. In comparison with frequentist trial designs, there are less established guidelines on how to report Bayesian trials. We provide a general overview on key components of the design, conduct, and analysis of Bayesian trials and elaborate on the reporting guidelines dos and don'ts. Copyright © 2020 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

Citation

J Jack Lee, Guosheng Yin. Principles and Reporting of Bayesian Trials. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2021 Jan;16(1):30-36

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PMID: 33229069

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