Disseminated histiocytic sarcoma in Asian palm civet (Paradoxurus hermaphroditus).

This case study had focused on a male, 7-year-old Asian palm civet (Paradoxurus hermaphroditus) with a history of biting its tail and the development of skin masses around its inguinal area, prior to its death. Macroscopically, multiple firm white nodular masses of 0.5-5 cm in diameter were found in the subcutis of the inguinal area, and in the lungs, spleen and liver. Microscopically, masses in the skin, lungs and spleen were composed of neoplastic spindle cells admixed with mononuclear cells and multinucleated giant cells. The neoplastic cells were arranged in a sheet pattern. Immunohistochemically, the neoplastic cells were immunohistochemically positive for vimentin, Iba-1, CD 204 and Human leukocyte antigen (HLA)-DR, while the cells were negative for cytokeratin and smooth muscle actin. Based on the histopathological and immunohistochemical results, disseminated histiocytic sarcoma was diagnosed.

Citation

Kittikorn Boonsri, Sakorn Dechkajorn, Kornravee Photichai, Saralee Srivorakul, Hassadin Boonsriroj, Atigan Thongtharb, Kidsadagon Pringproa. Disseminated histiocytic sarcoma in Asian palm civet (Paradoxurus hermaphroditus). The Journal of veterinary medical science. 2021 Jan 14;83(1):108-111

Mesh Tags

PMID: 33229793

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