Occlusive treatment enhances efficacy of tacrolimus 0.1% in a pediatric patient with severe alopecia areata: Case report and literature review.

César Bimbi, Georgia Kyriakou, Uwe Wollina

Pediatric dermatology 2021 Jan

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Tacrolimus is an immunomodulatory drug, available for topical and systemic treatment of several dermopathies that are characterized by immune dysregulation. In the case of alopecia areata, standard application has proven insufficient to yield satisfactory results. Herein, we present a 6-year-old patient with Down syndrome who was treated with topical tacrolimus 0.1% ointment under occlusion overnight with remarkable clinical improvement within 4 months. © 2020 Wiley Periodicals LLC.

Citation

César Bimbi, Georgia Kyriakou, Uwe Wollina. Occlusive treatment enhances efficacy of tacrolimus 0.1% in a pediatric patient with severe alopecia areata: Case report and literature review. Pediatric dermatology. 2021 Jan;38(1):339-340