Correlation Engine 2.0
Clear Search sequence regions


  • catalysis (1)
  • indoles (5)
  • Sizes of these terms reflect their relevance to your search.

    A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported. The protocol is based on the [3,3]-sigmatropic rearrangement of N-oxyenamines generated by the DABCO-catalyzed reaction of N-arylhydroxylamines and conjugated terminal alkynes, and delivers indoles endowed with a wide array of substitution patterns and topologies.

    Citation

    David Tejedor, Raquel Diana-Rivero, Fernando García-Tellado. A General and Scalable Synthesis of Polysubstituted Indoles. Molecules (Basel, Switzerland). 2020 Nov 28;25(23)

    Expand section icon Mesh Tags

    Expand section icon Substances


    PMID: 33260745

    View Full Text