Diverse Thiophenes as Scaffolds in Anti-cancer Drug Development: A Concise Review.

Neha V Bhilare, Pratibha B Auti, Vinayak S Marulkar, Vilas J Pise

Mini reviews in medicinal chemistry 2021

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Thiophenes are one of the abundantly found heterocyclic ring systems in many biologically active compounds. Moreover, various substituted thiophenes exert numerous pharmacological actions on account of their isosteric resemblance with compounds of natural origin, thus rendering them with diverse actions like antibacterial, antifungal, antiviral, anti-inflammatory, analgesic, antiallergic, hypotensives, etc. In this review, we specifically explore the chemotherapeutic potential of a variety of structures consisting of thiophene scaffolds as prospective anticancer agents. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Citation

Neha V Bhilare, Pratibha B Auti, Vinayak S Marulkar, Vilas J Pise. Diverse Thiophenes as Scaffolds in Anti-cancer Drug Development: A Concise Review. Mini reviews in medicinal chemistry. 2021;21(2):217-232