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    A 38-year-old woman presented for 18F-FDG PET/CT after multiple intra-abdominal surgical resections of a rare recurrent perivascular epithelioid cell tumor of the gastrointestinal tract. A solitary pelvic metastasis was detected, but surprisingly exhibited neither increased glucose consumption nor contrast enhancement on CT. Follow-up 18F-FDG PET/CT staging in the further disease course revealed multiple abdominal metastases, now, however, with markedly increased 18F-FDG uptake and intraoperatively correlating widespread peritoneal sarcomatosis. This case gives preliminary insight into monitoring of disease progression in metastatic perivascular epithelioid cell tumor, although the underlying pathophysiological bases for varying 18F-FDG uptake in PET/CT are not yet fully understood. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.


    Adrien Holzgreve, Matthias P Fabritius, Thomas Knösel, Bernhard W Renz, Lars H Lindner, Dorit Di Gioia, Peter Bartenstein, Johannes Rübenthaler, Reinhold Tiling. 18F-FDG PET/CT for Monitoring of Disease Progression in Metastatic Perivascular Epithelioid Cell Tumor. Clinical nuclear medicine. 2021 Feb 01;46(2):156-158

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    PMID: 33315683

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