High-sugar feeding and increasing cholesterol levels in infants.

Hypercholesterolaemia is an important risk factor for cardiovascular disease. Both total and LDL cholesterol levels are three-fold higher at the end of the first year of life and about four-fold higher in adulthood compared with the neonatal period. In the USA, only 25% of infants are exclusively breastfed and simple carbohydrate-rich formulas are preferentially consumed. Spikes in fasting glucose and insulin have been reported in formula-fed infants and are associated with higher levels of proprotein convertase subtilisin/kexin type 9, suggesting a potential link between high simple sugar intake and consequent increase in LDL cholesterol in early childhood. Published on behalf of the European Society of Cardiology. All rights reserved. © The Author(s) 2020. For permissions, please email: journals.permissions@oup.com.

Citation

Petra Zubin Maslov, Joseph A Hill, Thomas F Lüscher, Jagat Narula. High-sugar feeding and increasing cholesterol levels in infants. European heart journal. 2021 Mar 21;42(12):1132-1135

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PMID: 33326580

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