Successful treatment of a rare variant of mesangioproliferative glomerulonephritis with IgM deposits with Cyclosporin A].

D V Gurova, N V Chebotareva, A A Vinogradov, E V Stavrovskaya, L V Lysenko

Terapevticheskii arkhiv 2020 Jul 09

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We present a case with a rare variant of glomerulonephritis, IgM nephropathy, which occurs mainly with nephrotic syndrome. The clinical features of this variant of kidney damage are characterized; the pathogenetic and the transformation of this form of nephritis into focal segmental glomerulosclerosis are discussed. The development of severe nephrotic syndrome at the beginning of the disease, the formation of secondary steroid resistance have confirmed this hypothesis and have justified the treatment with cyclosporin A aimed at the recovery of the function of the podocyte with remission of nephritis.

Citation

D V Gurova, N V Chebotareva, A A Vinogradov, E V Stavrovskaya, L V Lysenko. Successful treatment of a rare variant of mesangioproliferative glomerulonephritis with IgM deposits with Cyclosporin A]. Terapevticheskii arkhiv. 2020 Jul 09;92(6):73-75