Advances in the studies of special biomarkers for the experimental diagnosis of CP/CPPS].

Cheng-Quan Ma, Jian Xiong, Hong-Jun Li

Zhonghua nan ke xue = National journal of andrology 2020 Jul

filter terms:

At present, there are no widely accepted specific biomarkers for the experimental diagnosis of chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS). Recent studies show that many related biomarkers exist in expressed prostatic secretions (EPS) or semen, urine and blood or serum. The monocyte chemotactic protein-1 (MCP-1/CCL-2), macrophage-inflammatory-protein-1 alpha (MIP-1α/CCL-3), interleukin-6 (IL-6), interleukin-8 (IL-8), nerve growth factor (NGF) and B7-H3 in EPS, prostatic exosomal protein (PSEP) in the urine, and prostate-specific antigen (PSA), mean platelet volume (MPV) and macrophage migration inhibitory factor (MIF) in the serum are believed to be of significant clinical and research value, and expected to become important laboratory biomarkers for the diagnosis of CP/CPPS.

Citation

Cheng-Quan Ma, Jian Xiong, Hong-Jun Li. Advances in the studies of special biomarkers for the experimental diagnosis of CP/CPPS]. Zhonghua nan ke xue = National journal of andrology. 2020 Jul;26(7):660-665