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    Reactive oxygen species (ROS) play a pivotal role in many cellular processes and can be either beneficial or harmful. The design of ROS-sensitive fluorophores has allowed for imaging of specific activity and has helped elucidate mechanisms of action for ROS. Understanding the oxidative role of ROS in the many roles it plays allows us to understand the human body. This review provides a concise overview of modern advances in the field of ROS imaging. Indeed, much has been learned about the role of ROS throughout the years; however, it has recently been shown that using nanoparticles, rather than individual small organic fluorophores, for ROS imaging can further our understanding of ROS. © 2021 by the Society of Nuclear Medicine and Molecular Imaging.


    Eli M Espinoza, Joachim Justad Røise, I-Che Li, Riddha Das, Niren Murthy. Advances in Imaging Reactive Oxygen Species. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2021 Apr;62(4):457-461

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    PMID: 33384322

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