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Anomalous aortic origin of a left coronary artery (L-AAOCA) with an intraseptal course is a rare anomaly and can be associated with myocardial ischemia and sudden cardiac death. No surgical or medical intervention is known to improve patient outcomes. A 7-year-old boy with intraseptal L-AAOCA presented with nonexertional chest pain, syncope, and had reversible myocardial ischemia on provocative testing. The patient was started on β-blockade, following which his symptoms improved and resolved over a period of six years. A follow-up dobutamine stress magnetic resonance imaging no longer showed reversible ischemia, and cardiac catheterization with fractional flow reserve did not show coronary flow compromise.

Citation

Tam T Doan, Athar M Qureshi, Shagun Sachdeva, Cory V Noel, Dana Reaves-O'Neal, Silvana Molossi. Beta-Blockade in Intraseptal Anomalous Coronary Artery With Reversible Myocardial Ischemia. World journal for pediatric & congenital heart surgery. 2021 Jan;12(1):145-148

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PMID: 33407035

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