An Update on Evaluation and Management in Cystinuria.

Sunil Daga, Victor Palit, James A Forster, Chandra Shekhar Biyani, Adrian D Joyce, Antonia Borissova Dimitrova

Urology 2021 Mar

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Cystinuria is the most common cause of inherited stone disease and is caused by the failure of absorption of filtered dibasic amino acids including cystine in the proximal tubules. It is associated with a very high recurrence rate in affected patients, with the potential for significant morbidity in such patients due to the need for repeated surgical interventions. A multimodal and multispecialty approach in a dedicated centre is the key to improving treatment outcomes and patient adherence to the treatment. This article reviews the latest knowledge on the clinical and diagnostic features and summarises key developments to aid clinicians in diagnosis and management options, together with future directions for the care of these patients. Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.

Citation

Sunil Daga, Victor Palit, James A Forster, Chandra Shekhar Biyani, Adrian D Joyce, Antonia Borissova Dimitrova. An Update on Evaluation and Management in Cystinuria. Urology. 2021 Mar;149:70-75