Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy.

Magnetic resonance imaging (MRI) has exquisite soft-tissue contrast and is the foundation for image guided radiotherapy (IGRT) with integrated magnetic resonance linacs. However, MRI suffers from geometrical distortions. In this study the MRI system- and patient-induced geometric distortion at four different tumor-sites was investigated: adrenal gland (7 patients), liver (4 patients), pancreas (6 patients), prostate (20 patients). Maximum level of total distortion within the gross-tumor-volume (GTV) was 0.96 mm with no significant difference between abdominal patients (adrenal gland, liver, pancreas) and pelvic patients (prostate). Total tumor-site specific distortion depended on location in the field-of-view and increased with the distance to MRI iso-center. © 2020 The Authors.

Citation

Signe Winther Hasler, Uffe Bernchou, Anders Bertelsen, Elisabeth van Veldhuizen, Tine Schytte, Vibeke Nordmark Hansen, Carsten Brink, Faisal Mahmood. Tumor-site specific geometric distortions in high field integrated magnetic resonance linear accelerator radiotherapy. Physics and imaging in radiation oncology. 2020 Jul;15:100-104

PMID: 33458333

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