Measurement of Lung Vessel and Epithelial Permeability In Vivo with Evans Blue.

Prestina Smith, Lauren A Jeffers, Michael Koval

Methods in molecular biology (Clifton, N.J.) 2021

filter terms:

Lung fluid balance is maintained in part by the barriers formed by the pulmonary microvasculature and alveolar epithelium. Failure of either of these barriers leads to pulmonary edema, which limits lung function and exacerbates the severity of acute lung injury. Here we describe a method using Evans Blue dye to simultaneously measure the function of vascular and epithelial barriers of murine lungs in vivo.

Citation

Prestina Smith, Lauren A Jeffers, Michael Koval. Measurement of Lung Vessel and Epithelial Permeability In Vivo with Evans Blue. Methods in molecular biology (Clifton, N.J.). 2021;2367:137-148