Hongchao Geng, Xiaoxu Chen, Leilei Sun, Yan Qiao, Jie Song, Sisi Shi, Qingyun Cai
Analytica chimica acta 2021 Feb 15A highly selective and sensitive photoelectrochemical (PEC) sensing platform was developed for kanamycin assay based on the aptamer modified sandwich-structured ZnCuInSe/Au/TiO2 nanowires. Sandwiched between the TiO2 nanowires and the ZnCuInSe quantum dot (QDs) layer, the Au nanoparticles (Au NPs) serves as a plasmonic photosensitizer and an electron relay, which expand the light absorption range and facilitates the charge transfer. Also, ZnCuInSe QDs, a broad spectrum photosensitizer can capture visible light, which enhance the photocurrent density response. Through the Au-S bond and Cu-S bond, the HS-aptamer were immobilized on the ZnCuInSe/Au/TiO2 nanowires as a recognition unit for kanamycin. The proposed sensing platform showed excellent assay performance for kanamycin with a linear response range from 0.2 to 250 nM, and high selectivity. By changing the recognizers, the proposed sensing platform could be easily extended to detect other biomolecules, and may have a promising application in bioanalysis. Copyright © 2020 Elsevier B.V. All rights reserved.
Hongchao Geng, Xiaoxu Chen, Leilei Sun, Yan Qiao, Jie Song, Sisi Shi, Qingyun Cai. ZnCuInSe/Au/TiO2 sandwich nanowires-based photoelectrochemical biosensor for ultrasensitive detection of kanamycin. Analytica chimica acta. 2021 Feb 15;1146:166-173
PMID: 33461712
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