Eosinophilic chronic rhinosinusitis and concurrent Kimura's disease treated with mepolizumab.

Jacqueline Ho, Sophie Walter, Richard J Harvey

BMJ case reports 2021 Jan 18

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Kimura's disease is a rare, benign, chronic inflammatory disorder characterised by its eosinophilic infiltrate. Patients often present with one or more progressively enlarging subcutaneous lymph nodes in the head and neck region or enlarging salivary glands. We describe the case of a 26-year-old man presenting with severe peripheral eosinophilia and upper airway inflammatory symptoms, who later developed cervical lymphadenopathy and formally diagnosed with Kimura's disease. Based on our English-language MEDLINE literature search, to our knowledge this is the first case report describing treatment of Kimura's disease with mepolizumab. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Citation

Jacqueline Ho, Sophie Walter, Richard J Harvey. Eosinophilic chronic rhinosinusitis and concurrent Kimura's disease treated with mepolizumab. BMJ case reports. 2021 Jan 18;14(1)