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A 60-year-old man with sigmoid colon cancer invading the urinary bladder underwent sigmoid colectomy and partial cystectomy. He developed headache and vomiting 12 weeks after surgery, and urgently hospitalized. Contrast MRI of head and whole spinal cord inspected no abnormality. CSF examination showed elevated CA19-9 20,551 U/mL, and the cytology revealed atypical cells similar to the sigmoid colon cancer cells. He was diagnosed as meningeal carcinomatosis, and received 1 course of CAPOX plus bevacizumab chemotherapy. He died 18 weeks after the surgery.

Citation

Sono Ito, Taiki Masuda, Hirotoshi Kobayashi, Fukuichiro Orita, Hideaki Iseki, Akisa Tsunemi. Meningeal Carcinomatosis of Sigmoid Colon Cancer-A Case Report]. Gan to kagaku ryoho. Cancer & chemotherapy. 2020 Dec;47(13):2216-2218

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PMID: 33468912

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