The versatility of liver X receptors in T cell homeostasis: Location, location, location

Nuclear receptors control the transcriptional program of target cells and thereby their phenotype and activities. Two complementary studies by Micheals et al. (https://doi.org/10.1084/jem.20201311) and Chan et al. (https://doi.org/10.1084/jem.20200318) published in JEM uncover the cell type-specific expression and role of the nuclear receptors liver X receptors in the regulation of T cell homeostasis and function. © 2021 Phan and Brunner.

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Truong San Phan, Thomas Brunner. The versatility of liver X receptors in T cell homeostasis: Location, location, location The Journal of experimental medicine. 2021 Apr 05;218(4)

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PMID: 33475707

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