Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity.

Min Wen, Chen Li, Mengyuan Zhang, Yan Sun, Fengming Liu, Xiaoyan Cui, Yongkui Shan

The Analyst 2021 Mar 07

filter terms:

A series of fluorescent molecular rotors, acridinium benzoates (Acr-A,B,C,D), were designed for ratiometrically monitoring cellular viscosity. High sensitivity to viscosity was observed in probe Acr-A with an insignificant steric effect in the acridinium nitrogen. Acr-A was employed to distinguish cancer cells from normal cells and track the dynamics of viscosity during cellular apoptosis.

Citation

Min Wen, Chen Li, Mengyuan Zhang, Yan Sun, Fengming Liu, Xiaoyan Cui, Yongkui Shan. Acridinium benzoates for ratiometric fluorescence imaging of cellular viscosity. The Analyst. 2021 Mar 07;146(5):1538-1542