Skincare Products as Sources of Mutagenic Exposure to Infants: An Imperative Study Using a Battery of Microbial Bioassays.

Amrita Nepalia, Anuradha Singh, Nupur Mathur, Rajashree Kamath, Smita Pareek, Maithili Agarwal

Archives of environmental contamination and toxicology 2021 Feb

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Infant skin is highly absorptive and sensitive to exposure from external agents (microbes, toxicants, heat, cold, etc.). Many specialized infant skincare products are currently commercially available. Although the manufacturers claim that their products are mild enough to suit the infant skin, these products need to be studied for their safety. Using animal models to examine the safety of the ever-increasing number of skincare products is not economically or logistically feasible. To overcome this problem, we suggest using a battery of microbial bioassays as a robust system for monitoring the mutagenic potential of skincare products. We picked popular infant skincare products from the Indian market and assessed them by using a battery of three microbial mutagenicity bioassays. Most of them showed significant and reproducible mutagenic potential. Our study results raise concerns about regular use of infant products and emphasize the need to enforce strict regulations for the manufacturing and safety assessment of infant products.

Citation

Amrita Nepalia, Anuradha Singh, Nupur Mathur, Rajashree Kamath, Smita Pareek, Maithili Agarwal. Skincare Products as Sources of Mutagenic Exposure to Infants: An Imperative Study Using a Battery of Microbial Bioassays. Archives of environmental contamination and toxicology. 2021 Feb;80(2):499-506