Neurosyphilis and the Jarisch-Herxheimer reaction: A therapy concern with HIV disease.

Rajendra Kapila, Robert A Schwartz

Dermatologic therapy 2021 Mar

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Jarisch-Herxheimer reaction (JHR) should be anticipated in treating neurosyphilis with coexistent human immunodeficiency virus (HIV) encephalitis. In that context we have devised a staging classification for JHR. In addition, an illustrative case is provided to emphasize the need to consider the diagnosis of neurosyphilis in HIV patients, and if delineated, to be prepared for a severe JHR. © 2021 Wiley Periodicals LLC.

Citation

Rajendra Kapila, Robert A Schwartz. Neurosyphilis and the Jarisch-Herxheimer reaction: A therapy concern with HIV disease. Dermatologic therapy. 2021 Mar;34(2):e14839