Standing By: How Intact Neurons React to Axon Injury.

Nerve injury affects the neurophysiology of severed and bystander axons. In this issue of Neuron, Hsu et al. demonstrate that this early effect is cell-autonomous and driven by dSarm, independently of its NADase activity otherwise required for axon degeneration. The authors show that axon injury signal spreads to intact neurons via glial cells. Copyright © 2021 Elsevier Inc. All rights reserved.

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Julia Schaeffer, Stephane Belin. Standing By: How Intact Neurons React to Axon Injury. Neuron. 2021 Feb 03;109(3):393-395

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PMID: 33539772

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