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The role of visible light on longevity is incompletely understood. Here we show the effect of visible light in Drosophila melanogaster is wavelength specific. Life span was significantly extended by green light, whereas blue light reduced longevity dramatically, and minor impact was observed with red light. While oxidative stress, heat stress, or caloric restriction does not contribute to the beneficial effect of green light, our study found that the life span extension effect of green light might be mediated by microbiota or photosensitive micronutrients in food medium. In conclusion, we report that green light can extend longevity and present the potential of light as a noninvasive therapy for aging-related diseases. Copyright © 2021 Elsevier Inc. All rights reserved.

Citation

Jie Shen, Peijing Yang, Xusheng Luo, Honglin Li, Yifan Xu, Jianying Shan, Zhizhang Yang, Boying Liang. Green light extends Drosophila longevity. Experimental gerontology. 2021 May;147:111268

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PMID: 33539986

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